Localization-Dependent and -Independent Roles of Numb Contribute to Cell-Fate Specification in Drosophila
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چکیده
منابع مشابه
Localization-Dependent and -Independent Roles of Numb Contribute to Cell-Fate Specification in Drosophila
During asymmetric cell division, protein determinants are segregated into one of the two daughter cells. The Numb protein acts as a segregating determinant during both mouse and Drosophila development. In flies, Numb localizes asymmetrically and is required for cell-fate specification in the central and peripheral nervous systems, as well as during muscle and heart development. Whether its asym...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2005
ISSN: 0960-9822
DOI: 10.1016/j.cub.2005.07.061